Weight Loss Peptides


This category includes peptides that regulate appetite, improve metabolic flexibility, and increase fat oxidation. They work through pathways like GLP-1, GIP, and glucagon receptors, or by enhancing mitochondrial energy output. These compounds help suppress hunger, improve blood sugar control, and promote sustainable fat loss while protecting lean muscle mass.

Introduction


Looking to shed extra weight and improve body composition? Peptide therapy offers an innovative approach. Peptides are naturally occurring compounds made from amino acids that play a crucial role in metabolism, fat burning, and energy balance. By leveraging targeted peptides, you can enhance fat reduction, appetite control, energy levels, and
muscle recovery.


Highlighted Peptides for Weight Loss


GLP/GIP Peptides


Tirz               – Dual GLP-1/GIP action with superior fat loss compared to GLP-1 alone.


Reta              – Triple agonist in research, enhances energy expenditure and weight loss.


Survodutide – Dual GLP-1/Glucagon agonist, under study for fat reduction


Growth Hormone Releasing Peptides

• Tesamorelin - A growth hormone–releasing hormone (GHRH) analog. It elevates GH and IGF-1, promoting fat metabolism and specifically reducing visceral adipose tissue. Tesamorelin also supports muscle preservation during fat loss. 

Ipamorelin – Selective GH release without raising cortisol, supports fat loss and recovery.


CJC-1295 – Long-acting GHRH analogue, boosts GH/IGF-1 for fat metabolism and muscle growth.

 

Other Fat-Loss Focused Peptides

AOD-9604 – GH fragment designed to promote visceral fat loss and metabolism.


AICAR – Improves endurance, stimulates fat oxidation, considered an 'exercise mimetic'.


5-Amino-1MQ – Inhibits NNMT, boosts NAD+ and metabolism, supports fat burning and energy.


MOTS-c – Mitochondrial peptide, enhances metabolic flexibility, fat oxidation, and insulin sensitivity.

 

Key Takeaways


• Peptides help regulate fat metabolism, lipolysis, and appetite, making them powerful tools for weight management.


• Benefits include enhanced fat burning, reduced fat storage, improved insulin sensitivity, better recovery, and improved sleep quality.


• Unlike many fat-burner products, peptides are considered safer with fewer side effects when used responsibly.


• Diet and exercise remain the foundation, but peptides can significantly accelerate results by aligning the body’s natural fat-burning pathways.