Cellular & Mitochondrial Health Peptides

This category targets the foundation of longevity—cellular energy, mitochondrial efficiency, and the repair systems that keep cells youthful and resilient. These peptides focus on restoring optimal energy production, reducing oxidative stress, and clearing out damaged or senescent cells. By improving mitochondrial performance and cellular signaling, they can support vitality, metabolic health, and healthy aging.

• Epithalon
  A synthetic tetrapeptide linked to telomerase activation and telomere length maintenance. It is studied for its potential to slow cellular aging, improve sleep regulation, and enhance overall longevity.

• FOXO4-DRI
  A peptide designed to selectively target and eliminate senescent “zombie” cells that drive inflammation and aging. By promoting senolysis, FOXO4-DRI may support tissue rejuvenation and extend healthy lifespan.

• MOTS-c
  A mitochondrial-derived peptide that activates AMPK, boosting glucose utilization, fat oxidation, and metabolic flexibility. MOTS-c enhances exercise performance and provides resilience against age-related metabolic decline.

• SS-31 (Elamipretide)
  A mitochondria-targeted peptide that binds cardiolipin, stabilizing mitochondrial membranes and improving ATP production. SS-31 reduces oxidative stress and has been studied for heart, muscle, and neuroprotective benefits.

• 5-Amino-1MQ
  A small molecule that inhibits NNMT (nicotinamide N-methyltransferase), an enzyme linked to reduced NAD+ availability. By restoring NAD+ levels, 5-Amino-1MQ supports cellular repair, mitochondrial function, and energy balance.

 

Key Takeaways

• These peptides work at the root level of health, targeting cells and mitochondria.
• Benefits include greater energy, improved metabolism, DNA protection. 
• By supporting mitochondrial and cellular health, they form the core foundation of longevity-based therapy.
• They may be used individually or synergistically as part of advanced anti-aging and performance protocols

Together, these peptides form a powerful toolkit for protecting cells from the hallmarks of ageing, enhancing mitochondrial output, and supporting long-term vitality and performance.